Manufacturing

Overview

Pharmagen Limited currently has three state of the art, dedicated and segregated plant facilities. These consist of a Semi Synthetic Penicillins Plant( SSP’s), A Semi Synthetic Cephalosporins Plant( SSC’s) Oral and Sterile, along with a Multi-Purpose General Product Manufacturing Plant( MPP’s).

Equipment

The production department has all the required equipment / machinery to run highly specialized operations. All equipment’s are CGMP compliant. Product contact parts are made of Stainless Steel 316, Teflon and glass. It is also ensured that equipment design and operational protocols facilitate efficient manufacturing and cleaning.

Environment Protection

Pharmagen Limited has designed its Manufacturing and Operational Protocols to minimize the impact on the environment.

1) Pharmagen Limited has its own dedicated Environment, Health and Safety Department with an ISO 45001 Certification. 2) Our Facilities have their own Waste Water Management system using a bio cleaning technique something that no plant in Pakistan has. 3) Our facilities control Air Pollution through a combination of our HVAC systems and an internal scrubbing system to control emissions. 4) Our facilities have an internal fire-fighting system. Our personell are regularly trained on how to respond in the case of an emergency

Manufacturing at a Glance

1. Semi Synthetic Penicillin’s (SSPs) Facility

Pharmagen's first project was the basic manufacture of Semi - Synthetic Penicillin’s (SSPs). The salient features of this project are as follows:

Commercial startup:1993

Products:1. AMOXYCILLIN TRIHYDRATE
2. AMPICILLIN TRIHYDRATE
3. CLOXACILLIN SODIUM
4. AMPICILLIN ANHYDROUS
5. FLUCLOXACILLIN SODIUM

2. Oral Semi Synthetic Cephalosporin’s (SSCs) Facility

The company's second project was the manufacture of oral (API's) cephalosporin’s in dedicated facility whose particulars are as below:

Commercial startup:2000

Products:1. CEPHRADINE
2. CEPHALEXIN
3. CEFADROXIL
4. CEFACLOR
5. CEFIXIME

3. Sterile Semi Synthetic Cephalosporin’s Sterile (SSCs) Facility

Commercial startup:2006

Products:1. CEPHRADINE L’ARGININE STERILE
2. CEFTRIAXONE SODIUM

4. Multi-Purpose Plant (MPP’s) Facility

The company's second project was the manufacture of oral (API's) cephalosporin’s in dedicated facility whose particulars are as below:

Commercial startup:2014

Products:1. CIPROFLOXACIN HYDROCHLORIDE
2. OMEPRAZOLE
3. SULFAMETHOXAZOLE
4. PYRAZINAMIDE
5. IBUPROFEN
6. SOFOSBUVIR

Separate Segregated and Dedicated Steriods Line1. BETAMETHAZONE
2. DEXAMETHAZONE

Highlights

  • Plants are designed to maintain separate materials and personnel flow.
  • Separate and dedicated manufacturing plants for Penicillin's, Cephalosporin's Steroid's and other products.
  • Quality, Health Safety and Environment systems are in place.
  • Plants has its own waste water treatment system which is being upgraded to Bio-cleaning technique
  • Plants Internal Environment is controlled through HVAC system
  • Emission are controlled through Scrubbing system
  • Plants has its own first line fire fighting system
  • Fire safety evacuation drills and Trainings on safety are carried out periodically

Environment, Health & Safety Policy

We at Pharmagen Limited are committed to protect the environment, ensure Occupational Health & Safety of our employees and all our associates and ensure the provision of amenities at our workplace. We manage our operations, activities, raw materials, manufacturing of Active Pharmaceutical Ingredients in safe, healthy and environment friendly manner. To fulfill legal and social responsibilities, we ensure continual improvement of our Safety and Environmental management systems by setting objectives regarding elimination of hazards, reduction of Health & Safety risks, prevention of workplace accidents & adverse environmental impacts. As a part of our commitment, we ensure staff consultation and participation, enhance Occupational Health, Safety and environmental awareness through safety trainings, Environment, Health & Safety Risk management, waste minimization, energy conservation, sustainable use of natural resources and seek justifiable measures to minimize the discharge of contaminants to the environment within permissible limits.

Quality Policy

"We all are committed for continual improvement in the competitiveness of our products (APIs), services and quality management system for better satisfaction of our customers and stakeholders. We ensure compliance to regulatory requirements, follow industry current good manufacturing practices and achieve our business goals through quality objectives. We are responsible for employee's development for their effective involvement to promote quality culture in the organization"