Ceftriaxone Sodium

CEFTRIAXONE SODIUM

Type of Drug:

Semi Synthetic Cephalosporin Derivate

Therapeutic Action and Use:

Broad Spectrum Antibiotic / Antibacterial.

Preparations:

Ceftriaxone Injection

Product Chemistry

Common Name:

Ceftriaxone Sodium

Chemical Name:

Disodium(6R,7R)-7-[[(Z)-(2-aminothiazol-4-yl)(methoxyimino)acetyl]amino]-3- [[(2-methyl-6-oxido-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)sulphanyl]methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Molecular Weight:

662

Molecular Formula:

C₁₈H₁₆N₈Na₂O₇S₃,3 ^1/₂ H₂O

Chemical Serail No:

(CAS No.) 104376-79-6

Packing:

10Kg in Sterile, air tight, temper proof Aluminium container

Storage:

Store below 25�C. Protect from light.

Shelf Life:

36 months

Related Substances:

i- Individual impurity:

Not more than 1.0%

ii- Total Impurities:

Not more than 4.0%

Sterility:

Meet the requirements

Bacterial Endotoxins:

Not more than 0.08 IU / mg

Contents:

* Ceftriaxone Sodium:

96 to 102 % w/w

Bulk Density(tapped):

Not less than 0.35g/ml
*(Based on anhydrous substances)

Pharmacopeial Quality:

USP, BP, EP

SPECIFICATIONS

Appearance:

A white to slightly yellowish, crystalline powder

Odor:

Characteristic

* Optical Rotation:

-155° to 170°

Water Contents:

8.0 to 11.0 % w/w.

pH Value:

6.0 to 8.0

N,N-Dimethylaniline:

Not more than 20 ppm